Natural Factors Echinamide Echinacea - Alcohol-Free - Natural Berry - Echinamide is the only echinacea extract clinically proven to increase immune response. When taken at the first sign of symptoms, it can help stop a cold from developing, ease symptoms, and accelerate healing. Backed by more than a decade of research, Echinamide has been clinically proven as an effective treatment for upper respiratory tract infections in multiple randomized, double-blind, placebo-controlled trials. Natural Factors Echinamide Echinacea Alcohol Free is ideal for those who want effective immune support without an alcohol base.